I get that question a lot. And the obvious quick answer is yes, of course I do. However, first time users are often not the most important users when it comes to various aspects of software and hardware development and design. You are only a first time user for a very limited time. The rest of the time you are an experienced user with the needs of an experienced user. That is why it is more important to design for when users become experienced and design to let them become experienced. That transition is probably the most difficult task is in usability design today.
However, this does not mean that first time users and inexperienced users are not important. It is just that people learn, adapt and want to do slightly new things with their software. If you do your work right, users stay beginners fort only a short period of time.